Well, my CD arrived yesterday, so I think I'm going to take the plunge this weekend.
I haven't even opened the CD yet, but after a bit of internet reading, apparently you have the option to "upgrade" and save your previous programs, or do a clean install over Vista, and have to reinstall everything. Fortunately, I've know about the upgrade since I got the laptop, so I haven't installed a lot of programs on this.
I've already backed-up my "can't lose" files onto my desktop, so I'm thinking I am going to do the "clean install".